Plain Language Samples : Before and After

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Sample #1

In plain language, describe the authorized use of Paxlovid.


Clinical, technical wording with a grade readability of 17 meaning college graduate and above

The FDA has authorized the emergency use of PAXLOVID, an investigational medicine, for the treatment of mild-to-moderate COVID-19 in adults and children (12 years of age and older weighing at least 88 pounds [40 kg]) with a positive test for the virus that causes COVID-19, and who are at high risk for progression to severe COVID-19, including hospitalization or death, under an EUA.

PAXLOVID is investigational because it is still being studied. There is limited information about the safety and effectiveness of using PAXLOVID to treat people with mild-to-moderate COVID‑19.”

Source: Above excerpt FOUND HERE on the Paxlovid manufacturer, Pfizer, website.


Translated into plain language with a grade readability of 9

Paxlovid fights the virus that causes Covid-19. The FDA is allowing the emergency use of Paxlovid. This means even though it is not fully approved, the benefits of its use are more important than the risks of full approval.

The medication needs a prescription from your doctor. If you test positive, then be sure to contact your doctor for more details as soon as possible.

Adults and children 12 and over must meet the below criteria to use it:


    • Positive Covid-19 test result and high risk

    • Children 12 and older must weigh at least 88 pounds

    • Take the medication less than 5 days of your positive test result

Sample #2

In plain language, advise emergency preparedness professionals concerning the dosing of Paxlovid and its interaction profile.


Paxlovid consists of two separate medications taken together. Take 6 Paxlovid pills orally per day for 5 days. Pick up your prescription at stocking community pharmacies. You can refer to the Paxlovid website for common drug-drug and drug-disease reactions. Store in ambient temperatures and be sure to follow up directly with your prescriber for any questions and monitoring.


A prescription is required to get Paxlovid and you can receive it from the pharmacy. Not all pharmacies have Paxlovid in stock, so be sure to consult with your doctor for the nearest available location.

Paxlovid consists of two different medications called nirmatrelvir and ritonavir.

Take 2 pink nirmatrelvir tablets and 1 white ritonavir tablet at the same time orally in the morning and repeat this again in the evening. Do this every day for 5 days. This is the standard dose and may differ if you have kidney problems.  

There are many drug interactions and other health conditions that may conflict with this medication, but not all of them may apply to you. It’s best to speak to your pharmacist and doctor to see if this medication is a good fit for you.

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